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Professor Charlotte A. E. Hauser

Principal Investigator
​Professor​​ of Bioscience

Research Interests

Professor Hauser’s research interests align at the interfaces between chemistry, biomedicine, bioengineering and nanotechnology. Focus is on the development of platform technologies, using smart nanomaterials for regenerative, biomedical and environmental applications.
Her interest refers to the rational molecular design, synthesis and mechanistic understanding of novel supramolecular structures. Investigated systems include peptide-based nanostructures with an innate propensity to self-assemble to biomimetic architectures applicable for biomedical applications such as cell substrates, sensors and 3D tissue scaffolds for regenerative medicine. Bottom-up nanofabrication is a powerful tool for the development of functional tissue equivalents, organotypic tissues and devices. Moreover, these biomimetic supramolecular constructs will be used for the design and fabrication of novel organ-on-a-chip devices and disease models.
Furthermore, Professor Hauser is interested in 3D bioprinting, using supramolecular organotypic constructs to fabricate high-throughput platforms for drug screening, pathogen detection and other diagnostic purposes. Synthetic biology approaches are explored for the generation of functional biomaterial.

Selected Publications

Y. Loo, A. Lakshmanan, M. Ni, L.L. Toh, S. Wang and C.A.E. Hauser
Nano Letters, 15 (2015) 6919-6925
 
Y. Loo, Y.C. Wong, E.Z. Cai, C.H. Ang, A. Raju, A. Lakshmanan, A.G. Koh, H.J. Zhou, T.C. Lim, S.M. Moochhala and C.A.E. Hauser
Biomaterials, 35 (2014) 4805-4814
 
M.R. Reithofer, A. Lakshmanan, A.T.K. Ping, J.M. Chin and C.A.E. Hauser
Biomaterials, 35 (2014) 7535-7542
 
M.R. Reithofer, K.H. Chan, A. Lakshmanan, D.H. Lam, A. Mishra, B. Gopalan, M. Joshi, S. Wang, and C.A.E. Hauser
Chemical Science, 5 (2014) 625-630
 
W.Y. Seow and C.A.E. Hauser
Advanced Healthcare Materials, 2 (2013) 1219-1223
 
A. Lakshmanan, D.W. Cheong, A. Accardo, E. Di Fabrizio, C. Riekel, and C.A.E. Hauser
Proceedings of the National Academy of Sciences, 110 (2013) 519-524
 
A. Lakshmanan, S. Zhang, C.A.E. Hauser
Trends in Biotechnology, 30 (2011) 155-165
 
A. Mishra, Y. Loo, R. Deng, Y.J. Chuah, H.T. Hee, J.Y. Ying and C.A.E. Hauser
Nano Today, 6 (2011) 232-239
 
C.A.E. Hauser, R. Deng, A. Mishra, Y. Loo, U. Khoe, F. Zhuang, D.W. Cheong, A. Accardo, M.B. Sullivan, C. Riekel, J.Y. Ying, and U.A. Hauser
Proceedings of the National Academy of Sciences, 108 (2011) 1361-1366

Education

  • Ph.D., University of Cologne, Germany, 1990
  • M.Sc., Chemistry, University of Cologne, 1986
  • B.Sc., Chemistry, University of Cologne, Germany, 1983
  • B.Sc., Physics, University of Cologne, Germany,1980

KAUST Affiliations