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Total result(s) found: 42
  • ​Towards biologically relevant synthetic designer matrices in 3D bioprinting for tissue engineering and regenerative medicine
    R.M. Costa, S. Rauf, C.A.E. Hauser
    In Press, Accepted Manuscript, 2017
Keywords:
3D bioprinting, Bioinks, Synthetic scaffolds, Tissue reconstruction, Hydrogels, Scaffold functionalization, Biomedical engineering
  • ​Transparent crosslinked ultrashort peptide hydrogels as a carrier dressing with high shape fidelity to accelerate healing of full-thickness excision wounds
    W.Y. Seow, G. Salgado, E.B. Lane, and C.A.E. Hauser   
    Scientific Reports 6 (2016), 32670
Keywords:
Peptide hydrogels, High shape fidelity, Excision wounds, Human body
  • ​Freeze-dried agarose gels: A cheap, simpe and recyclable adsorbent for the purification of methylene blue from industrial wastewater
    W.Y. Seow and C.A.E. Hauser
    Journal of Environmental Chemical Engineering 4 (2016) 1714-1721
Keywords:
Adsorption, Agarose hydrogel, Freeze dry, Methylene blue, Textile and industrial wastewater, Water purification
  • ​Roadmap on biosensing and photonics for nanomedicine
    E. Di Fabrizio, S. Schlücker, J. Wenger, R. Regmi, H. Rigneault, G. Calafiore, M. West, S. Cabrini, M. Fleischer, N. van Hulst, M.F. Garcia-Parajo, A. Pucci, D. Cojoc, C.A.E. Hauser, and M. Ni
    Journal of Optics 18 (2016) 063003
Keywords:
Biophotonics, Biosensing, Nanomedicine, Nanophotonics, Plasmonics
  • ​Bioprinting synthetic self-assembling peptide hydrogels for biomedical applications
    Y. Loo and C.A.E. Hauser
    Biomedical Materials 11 (2016) 014103
Keywords:
Biomaterial, Hydrogel, Nanofiber, Peptide
  • ​Probing droplets with biological colloidal suspensions on smart surfaces by synchrotron radiation micro- and nano-beams
    G. Marinaro, A. Accardo, N. Benseny-Cases, M. Burghammer, H. Castillo-Michel, M. Cotte, S. Dante, F. De Angelis, E. Di Cola, E. Di Fabrizio, C. Hauser and C. Riekel
    Optics and Lasers in Engineering 76 (2016) 57-63
Keywords:
Biological colloids, Digital microfluidics, Micro-/nano X-ray diffraction, MicroFTIR, Synchrotron radition
  • ​3D bioprinting technology for regenerative medicine applications
    D. Sundaramurthi, S. Rauf, and C.A.E. Hauser
    International Journal of Bioprinting, 2 (2016) 9-16
Keywords:
Bioprinting, Bioinks, Cells, Hydrogels, Scaffolds, Organ transplantation
  • Tumor-derived circulating endothelial cell clusters in colorectal cancer
    I. Cima, S.L. Kong, (...), C.A.E. Hauser, R.M. van Dam, W.-Y. Lim, S. Prabhakar, B. Lim, P.K. Koh, P. Robson, J.Y. Ying, A.M. Hillmer, and M.-H. Tan
    Science Translational Medicine 8 (2016) 345ra8
Keywords:
Cancer, Early detection, Colorectal cancer, Liquid biopsy, Circulating tumor cells, Translational medicine
  • ​Peptide bioink: self-assembling nanofibrous scaffolds for 3d organotypic cultures
    Y. Loo, A. Lakshmanan, M. Ni, L.L. Toh, S. Wang, and C.A.E. Hauser
    Nano Letters 15 (2015) 6919-6925
Keywords:
Bioprinting, Nanofibrous scaffold, Peptide bioink, Smart biomaterials, Stimuli-responsive self-assembly, Ultrashort peptides
  • Self-assembled proteins and peptides as scaffolds for tissue regeneration
    Y. Loo, M. Göktaş, A.B. Tekinay, M.O. Guler, C.A.E. Hauser, and A. Mitraki
    Advanced Healthcare Materials 4 (2015) 2557-2586
Keywords:
Peptides, Proteins, Rational design, Scaffolds, Self-assembly, Tissue engineering
  • Synthesis and bioactivity of a conjugate composed of green tea catechins and hyaluronic acid
    F. Lee, J. Lim, M.R. Reithofer, S.S. Lee, J.E. Chung, C.A.E. Hauser and M. Kurisawa
    Polymer Chemistry, 6 (2015) 4462-4472
Keywords:
Bioactivity; Biocompatibility; Isomers; Mass spectrometry, Nuclear magnetic resonance spectroscopy, Organic acids, Tissue engineering
  • ​The wonder stuff – How peptide hydrogels could change the face of biomedicine
    K.H. Chan, Jaspreet and C.A.E. Hauser
    Laboratory News, (2015)
Keywords:
Peptide hydrogels, Biomedicine, Human body
  • ​In situ synthesis of size-controlled, stable silver nanoparticles within ultrashort peptide hydrogels and their anti-bacterial properties
    M.R. Reithofer, A. Lakshmanan, A.T.K. Ping, J.M. Chin and C.A.E. Hauser
    Biomaterials, 35 (2014) 7535-7542
Keywords:
Silver, Nanoparticle, Peptide, Hydrogel, Self-assembly, Anti-bacterial
  • ​De novo design and experimental characterization of ultrashort self-associating peptides
    J. Smadbeck, K.H. Chan, G.A. Khoury, B. Xue, R.C. Robinson, C.A.E. Hauser, and C.A. Floudas
    PLOS Computational Biology 10 [7] (2014) e1003718
Keywords:
Computational protein design, Sequence selection problem, Amyloid fibril formation, Atomic-level accuracy, Mean-field theory, Cross-beta spine, Flexible templates, Combinatorial libraries, Biological-materials, Compstatin variants
  • ​Creation of consistent burn wounds: a rat model
    E.Z. Cai, C.H. Ang, A. Raju, K.B. Tan, E.C.H. Hing, Y. Loo, Y.C. Wong, H. Lee, J. Lim, S.M. Moochhala, C.A.E. Hauser, and T.C. Lim
    Archives of Plastic Surgery, 41 (2014) 317-324
Keywords:
Animals, Burns, Rats wound healing
  • ​Self-assembled peptide nanostructures for regenerative medicine and biology
    M. Ni and C.A.E. Hauser
    In Micro- and Nano-Fabrication Using Self-Assembled Biological Nanostructures, J. Castillo-Leon and W. Svendsen ed., Elsevier, 2014
Keywords:
Peptide nanofibers, Peptide nanotubes, Ultrashort peptides, Tissue engineering scaffolds, Drug delivery vehicles, Peptide therapeutics
  • ​Highlight on: P-Glycoprotein-dependent trafficking of nanoparticle-drug conjugates
    K.H. Chan and C.A.E. Hauser
    Materials View, 2014  
Keywords:
P-Glycoprotein-dependent, Nanoparticle-drug conjugates, Nanoparticles,
  • ​Amyloid-based nanosensors and nanodevices
    C.A.E. Hauser, S. Maurer-Stroh and I.C. Martins
    Chemical Society Reviews, 43 (2014) 5326-45
Keywords:
Fibril-forming segments, Dip-pen nanolithography, X-ray-diffraction, Alzheimers-disease, Peptide nanotubes, Carbon nanotubes, Molecular-basis, Globular-proteins
  • ​Short to ultrashort peptide hydrogels for biomedical uses
    W.Y. Seow and C.A.E. Hauser
    Materials Today 17 (2014), 381–388
Keywords:
Self-assembling peptide, Beta-sheet tapes, Amphiphile nanofibers, Hyaluronic-acid, Complementary oligopeptide, Mechanical-properties, Gelation properties, Amyloid fibrils, Cell-culture
  • ​Ultrashort peptide nanofibrous hydrogels for the acceleration of healing of burn wounds
    Y. Loo, Y.C. Wong, E.Z. Cai, C.H. Ang, A. Raju, A. Lakshmanan, A.G.W. Koh, H.J. Zhou, T.C. Lim, S.M. Moochhala, and C.A.E. Hauser
    Biomaterials, 35 (2014) 4805-14
Keywords:
Ultrashort peptide hydrogels, Nanofibers, Self-assembly, Partial thickness burns, Wound healing
  • ​Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy
    M.R. Reithofer, K.-H. Chan, A. Lakshmanan, D.H. Lam, A. Mishra, B. Gopalan, M. Joshi, S. Wang, and C.A.E. Hauser
    Chemical Science, 5 (2014) 625-630
Keywords:
Hydrogel matrices, Cancer-chemotherapy, Colorectal-cancer, Targeted delivery, Carbon nanotubes, Controlled-trial, Platinum drugs, Pharmacokinetics
  • Influence of metal salts on the hydrogelation properties of ultrashort aliphatic peptides
    A. Mishra, K.-H. Chan, M.R. Reithofer, and C.A.E. Hauser
    RSC Advances, 3 (2013) 9985-9993
Keywords:
Self-assembling peptide, Hofmeister series, Spectroscopy, Stability, Scaffolds, Coordination, Biomaterials
  • ​Tunable mechanical properties of ultrasmall peptide hydrogels by crosslinking and functionalization to achieve the 3D distribution of cells
    W.Y. Seow and C.A.E. Hauser
    Advanced Healthcare Materials, 2 (2013) 1219-1223
Keywords:
Ultrasmall peptides, Hydrogel, Disulfide bonds, 3D environment, Crosslinking
  • ​A convenient and minimally-invasive method to study gel formation by surface tension measurements
    W.Y. Seow and C.A.E. Hauser
    Journal of Chemical Science and Technology, 2 (2013) 88-92
Keywords:
Hydrogel; Gelation Kinetics; Surface Tension; Gel Formation
  • ​Oxidation as a facile strategy to reduce the surface charge and toxicity of polyethyleneimine gene carriers
    W.Y. Seow, K. Liang, M. Kurisawa, and C.A.E. Hauser
    Biomacromolecules, 14 (2013) 2340-2346
Keywords:
Poly(ethylenimine), Degradation, Efficiency, Peptides, Vector, Cells
  • Aliphatic peptides show similar self-assembly to amyloid core sequences, challenging the importance of aromatic interactions in amyloidosis
    A. Lakshmanan, D.W. Cheong, A. Accardo, E. Di Fabrizio, C. Riekel, and C.A.E. Hauser
    PNAS, 110[2] (2013) 519-524
Keywords:
Fibril formation, Structural-characterization, Polypeptide iapp, Building-blocks, X-ray, Nanostructures, Transthyretin, Oligomers, Proteins
  • ​Peptide hydrogels support stem cell applications in regenerative medicine
    C.A.E. Hauser and Y. Loo
    Gynäkologische Endokrinologie, 10 (2012) 255-264
Keywords:
Pluripotent stem cells, Embryonic stem cells, Hydrogels, Peptides, Cell culture
  • ​Self-assembling peptides as cell-interactive scaffolds
    E.C. Wu, S. Zhang, and C.A.E. Hauser
    Advanced Functional Materials, 22[3] (2011) 456-468
Keywords:
Self-assembly, Peptides, Scaffold, Tissue engineering
  • Short self-assembling peptides as building blocks for modern nanodevices
    A. Lakshmanan, S. Zhang, C.A.E. Hauser
    Trends in Biotechnology, 30[3] (2011) 155-165
Keywords:
Ionic-complementary peptide, Nanoparticle superstructures, Nanotechnological applications, Diphenylalanine nanotubes, Amphiphile nanofibers, Modified electrodes, Manipulation
  • ​From short peptides to nanofibers to macromolecular assemblies in biomedicine
    Y. Loo, S. Zhang and C.A.E. Hauser
    Biotechnology Advances, 30[3] (2011) 593-603
Keywords:
Hydrogels, Self-assembling peptide motifs, Fibril formation, Supramolecular architecture, Regenerative medicine
  • ​Self-Assembling peptide surfactants A6K and A6D Adopt α-helical structures useful for membrane protein stabilization
    K. Oglęcka, F. Zhuang, and C.A.E. Hauser
    Membranes, 1 (2011) 314-326
Keywords:
Fiber diffraction, Molecular dynamics simulation, Self-assembly mechanism, Supramolecular peptide scaffolds, Ultrasmall peptides
  • ​Ultrasmall peptides self-assemble into diverse nanostructures: morphological evaluation and potential implications
    A. Lakshmanan and C.A.E. Hauser
    International Journal of Molecular Sciences, 12 (2011) 5736-5746
Keywords:
Ultrasmall peptides, Self-assembly, Bioengineering, Nanotechnology, Supramolecular structures, Origin of life
  • ​The effect of thiol functional group incorporation into cationic helical peptides on antimicrobial activities and spectra
    N. Wiradharma, M. Khan, L.-K. Yong, C.A.E. Hauser, S.V. Seow, S. Zhang, Y.-Y. Yang
    Biomaterials, 32 (2011) 9100-9108
Keywords:
Antimicrobial peptides (AMP), alpha-Helix, Thiol and sulfhydryl, Membrane lysis, Hemolysis, Drug resistance
  • ​Ultrasmall natural peptides self-assemble to strong temperature-resistant helical fibers in scaffolds suitable for tissue engineering
    A. Mishra, Y. Loo, R. Deng, Y.J. Chuah, H.T. Hee, J.Y. Ying and C.A.E. Hauser
    NanoToday, 6 (2011) 232-239
Keywords:
Ultrasmall peptides, Self-assembly, Hydrogels, Tissue engineering
  • Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents
    N. Wiradharma, U. Khoe, C.A.E. Hauser, S.V. Seow, S. Zhang, and Y.Y. Yang
    Biomaterials, 32 (2011) 2204-2212
Keywords:
α-Helix, Antimicrobial peptides (AMP), Hemolysis, Membrane lysis, Minimum inhibitory concentration (MIC)
  • Natural tri- to hexapeptides self-assemble in water to amyloid β-type fiber aggregates by unexpected α-helical intermediate structures
    C.A.E. Hauser, R. Deng, A. Mishra, Y. Loo, (...), A. Accardo, M.B. Sullivan, C. Riekel, J.Y. Ying, and U. Hauser
    PNAS, 108 (2011) 1361–1366
Keywords:
Self-assembly mechanism, Ultrasmall peptides, Supramolecular peptide scaffolds, Fiber diffraction, Molecular dynamics simulation
  • ​Peptides as biological semiconductors
    C.A.E. Hauser, S. Zhang
    Nature, 468 (2010) 516-517
Keywords:
Quantum confinement, Nanotubes
  • ​Designer self-assembling peptide nanofiber biological materials
    C.A.E. Hauser, S. Zhang
    Chem. Soc. Rev. 39 (2010) 2780-2790
Keywords:
Surfactant-like peptides, Complementary oligopeptide, Beta-sheet, Endothelial-cells, Form nanotubes, In-vitro, scaffolds, Hydrogel, Differentiation, Nanovesicles
  • ​Study of bioengineered zebra fish olfactory receptor 131-2: receptor purification and secondary structure analysis
    K.-J. Leck, S. Zhang and C.A.E. Hauser
    PLoS One, 5 [11] (2010) 2780-2790
Keywords:
HEK293S tetracyclineinducible system, G protein coupled receptor, Zebra fish receptor
  • ​Molecular self-assembly and applications of designer peptide amphiphiles
    X. Zhao, F. Pan, H. Xu, C.A.E. Hauser, S. Zhang, and J.R. Lu
    Chem. Soc. Rev. 39 (2010) 3480-3498
Keywords:
Peptide fragments, Biocompatible materials, Nanomaterials, Surface-active agents
  • Designer self-assembling peptide materials for diverse applications
    C.A.E. Hauser, S. Zhang
    Macromol. Symp. 295 (2010) 30-48
Keywords:
3D cell cultures, Ionic self-complementary peptides, Lipid-like peptides, Molecular self-assembly, Stabilizing membrane proteins, Tissue regeneration
  • ​Development of a small molecule peptidomimetic affinity ligand for efficient purification of the large protein factor VIII
    S. Knör, B. Laufer, A.V. Khrenov, A. Benhida, S.C. Grailly, N. Beaufort, V. Magdolen, C.A.E. Hauser, E.L. Saenko, J.-M.R. Saint-Remy, H. Kessler
    Adv. Exp. Med. Biol., 611 (2009) 151-152
Keywords:
Protein purification, Ligand binding, Protein degradation, Peptides