Researchers from the King Abdullah University of Science and Technology (KAUST) have developed a new method of 3D printing hydrogel scaffolds based on ultrashort peptides.

Peptides are short chains of amino acids, which form the building blocks of proteins. The researchers used ultrashort peptides as the basis of their newly developed ink which can be 3D printed to form hydrogels containing cells. 

Led by KAUST bioengineer Charlotte Hauser, the team are seeking to address challenges surrounding shape stability in 3D printed hydrogels without the use of harsh chemicals or ultraviolet light that threaten cell survival.

“It’s challenging to find a cell-friendly biomaterial that supports long-term cell survival and is also printable,” said KAUST PhD student Hepi Hari Susapto. “Our bioinks made from self-assembling ultrashort peptide hydrogels efficiently address this challenge.”

The newly developed bioprinting technique has the potential to revolutionize tissue engineering and regenerative medicine. Photo via KAUST.

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