Manola Moretti, PhD

Research Scientists


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Research Interests

​Dr. Moretti's main field of research is the characterization of biolgical samples by means of AFM imaging, Raman spectroscopy, AFM force spectroscopy and TERS spectroscopy, starting from DNA, protein, to living cells. The ultimate objective of her work is to achieve nanometer resolution chemical information by Raman spectroscopy coupled with AFM imaging.

Selected Publications

  • Confined laminar flow on a super-hydrophobic surface drives the initial stages of tau protein aggregation. Microelectronic engineering
    M. Moretti, M. Allione, M. Marini, A. Giugni, B. Torre, G. Das, and E. Di Fabrizio Proceedings of Micro-Nano Engineering International Conference, 18-22 Sept. 2017, Braga, Portugal

  • Raman study of lysozyme amyloid fibrils suspended on super-hydrophobic surfaces by shear flow. Microelectronic engineering
    M. Moretti, M. Allione, M. Marini, B. Torre, G. Das, and E. Di Fabrizio
    Proceedings of Micro-Nano Engineering International Conference, 19-23 Sept. 2016, Vienna, Austria, Vol. 178, pp. 194–198

  • Graphene: A building foundation for efficient plasmonic SERS device
    Das, G., Moretti, M., Torre, B., Allione, M., Giugni, A., Fabrizio, E.D.
    Biochemistry & Analytical Biochemistry 2017, 06 (01)

  • Imaging and structural studies of DNA–protein complexes and membrane ion channels
    Marini, M., T. Limongi, A. Falqui, A. Genovese, M. Allione, M. Moretti, S. Lopatin, L. Tirinato, G. Das, B. Torre, A. Giugni, F. Cesca, F. Benfenati, E. Di Fabrizio Nanoscale, (2017), vol. 9(8), pp. 2768-2777

  • Tip enhanced raman spectroscopy of rhodamine 6G on nanostructured gold substrate
    Moretti, M., G. Das, B. Torre, M. Allione, and E. Di Fabrizio
    Optics and Lasers in Engineering, (2016), vol.76, pp. 52-56

  • The structure of DNA by direct imaging
    M. Marini, A. Falqui, M. Moretti, T. Limongi, M. Allione, A. Genovese, S. Lopatin, L. Tirinato, G. Das, B. Torre, A. Giugni, F. Gentile, P. Candeloro, and E. Di Fabrizio
    Science Advances. Vol. 1, No.7, (2015)

  • Visualization of single proteins from stripped native cell membranes: a protocol for high- resolution atomic force microscopy
    C. Marasini, E. Jacchetti, M. Moretti, C. Canale, O. Moran and M. Vassalli
    Microscopy Research and Technique, (2013), vol. 76, (no.7), pp. 723-732

  • Reflection-mode TERS on insulin amyloid fibrils with top-visual AFM probes
    M. Moretti, R. Proietti Zaccaria, E. Descrovi, G. Das, M. Leoncini, C. Liberale, F. De Angelis, and E. Di Fabrizio
    Plasmonics (2013), vol. 8, (no. 1), pp. 25-33

  • Direct Imaging of DNA Fibers: The Visage of Double Helix
    F. Gentile, M. Moretti, T. Limongi, A. Falqui, G. Bertoni, A. Scarpellini, S. Santoriello, L. Maragliano, R. Proietti Zaccaria and E. Di Fabrizio
    Nano Letters (2012), vol. 12, (no. 12), pp. 6453-8

  • Breaking the diffusion limit with super-hydrophobic delivery of molecules to plasmonic nanofocusing SERS structures
    F. De Angelis, F. Gentile, F. Mecarini, G. Das, M. Moretti, P. Candeloro, M.L. Coluccio, G. Cojoc, A. Accardo, C. Liberale, R. Zaccaria Proietti, G. Perroziello, G. Cuda, R. Cingolani and E. Di Fabrizio
    Nature Photonics (2011), vol. 5, pp. 682-687


  • Ph.D., Nanotechnology, University of Trieste, Italy, 2008​​
  • M.Sc., Biotechnology, Udine, Italy, 2002​
  • B.Sc., Agriculture, Udine, Italy, 2000

Professional Profile

  • ​2019-presnt: Postdoctoral Fellow: Laboratory of Nanomedicine, BESE, KAUST, Thuwal, Saudi Arabia
  • 2014- 2019: Postodoctoral fellow, SMILEs Laboratory, PSE, KAUST, Thuwal, Saudi Arabia
  • 2010-2014: Postodoctoral Fellow: IIT, Genova, Italy
  • 2009-2011: Visiting scientist: Molecular Foundry, LBNL, Berkeley, California, USA
  • 2008-2009: Postdoctoral Fellow: CalMed SRL, Catanzaro, Italy​

Research Interests Keywords

AFM imaging Raman spectroscopy of bio-samples

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