Group Photo Nanomedicine Lab KAUST

Panagiotis Bilalis, PhD

Research Scientists


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Research Interests

Dr. Bilalis' research interests are in the field of biomaterials where many interdisciplinary fields such as polymer chemistry, drug delivery, and nanotechnology intersect.

Selected Publications

Nanodesigned magnetic polymer containers for dual stimuli actuated drug-controlled release and magnetic hyperthermia mediation 
P. Bilalis, A. Chatzipavlidis, L.A. Tziveleka, N. Boukos, and G. Kordas 
J. Mater. Chem., 22, 13451-13454, 2012 
Nanostructuring the surface of dual responsive hollow polymer microspheres for versatile utilization in nanomedicine-related applications 
A. Chatzipavlidis, P. Bilalis, L.A. Tziveleka, N. Boukos, C.A. Charitidis, G. Kordas 
Langmuir, 29, 9562-9572, 2013 
Development of multiple stimuli responsive magnetic polymer nanocontainers as efficient drug delivery systems 
L.A. Tziveleka, P. Bilalis, A. Chatzipavlidis, N. Boukos, and G. Kordas 
Macromol. Biosci., 14, 131-141, 2014 
Controlled polymerization of histidine and synthesis of well-defined stimuli responsive polymers. Elucidation of the structure–aggregation relationship of this highly multifunctional material 
D. Mavrogiorgis, P. Bilalis, A. Karatzas, D. Skoulas, G. Fotinogiannopoulou, H. Iatrou 
Polym. Chem., 5, 6256-6278, 2014 
Self-assembly of a model peptide incorporating a hexa-histidine sequence attached to an oligo-alanine sequence, and binding to gold NTA/Nickel nanoparticles 
I. Hamley, S. Kirkham, A. Dehsorkhi, V. Castelletto, J. Adamcik, R. Mezzenga, J. Ruokolainen, C. Mazzuca, E. Gatto, M. Venanzi, E. Placidi, P. Bilalis, H. Iatrou 
Biomacromolecules, 15, 3412−3420, 2014
Preparation of hybrid triple-stimuli responsive nanogels based on poly(L-Histidine) 
P. Bilalis, S. Varlas, A. Kiafa, A. Velentzas, D. Stravopodis, H. Iatrou 
J. Polym. Sci. Polym. Chem., 54, 1278-1288, 2016
Self-assembly of telechelic tyrosine end-capped PEO and poly(alanine) polymers in aqueous solution 
S. Kirkham, V. Castelletto, I. William Hamley, M. Reza, J. Ruokolainen, D.H. Merino, P. Bilalis, H. Iatrou 
Biomacromolecules, 17, 1186−1197, 2016
pH-Sensitive nanogates based on poly(L-histidine) for controlled drug release from mesoporous silica nanoparticles 
P. Bilalis, L.-A. Tziveleka, S. Varlas, H. Iatrou 
Polym. Chem., 7, 1475–1485, 2016
Self-healing pH- and enzyme stimuli-responsive hydrogels for targeted delivery of gemcitabine to treat pancreatic cancer 
P. Bilalis, D. Skoulas, A. Karatzas, J. Marakis, A. Stamogiannos, C. Tsimblouli, E. Sereti, E. Stratikos, K. Dimas, D. Vlassopoulos, H. Iatrou 
Biomacromolecules, 19, 3840−3852, 2018
Poly(sarcosine)-based nano-objects with multi-protease resistance by aqueous photoinitiated polymerization-induced self-assembly (Photo-PISA) 
S. Varlas, P.G. Georgiou, P. Bilalis, J.R. Jones, N. Hadjichristidis, R.K. O’Reilly 
Biomacromolecules, 19, 4453−4462, 2018


  • ​Ph.D., Polymer Science, Chemistry Department, University of Athens, Greece, 2008
  • M.Sc., Polymer Science, Chemistry Department, University of Athens, Greece, 2005
  • B.Sc., Chemistry, University of Patras, Greece, 2003​

Professional Profile

  • 2015-present: Research Scientist, KAUST, Thuwal, Saudi Arabia.
  • 2013-2015: Post-doctoral fellow at University of Athens, Chemistry Department in a program entitled: «Synthesis of multifunctional amphiphilic hybrid Polypeptides that form smart drug and gene delivery nanoconstructs against pancreatic cancer».
  • 2009-2012: Post-doctoral fellow at NCSR Demokritos Research Center, Greece, in a program called: “A Novel Nano-container drug carrier for targeted treatment of prostate cancer”.

Research Interests Keywords

Material chemistry Polypeptides Biomaterials

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