​Probing droplets with biological colloidal suspensions on smart surfaces by synchrotron radiation micro- and nano-beams

by G. Marinaro, A. Accardo, N. Benseny-Cases, M. Burghammer, H. Castillo-Michel, M. Cotte, S. Dante, F. De Angelis, E. Di Cola, E. Di Fabrizio, C. Hauser, And C. Riekel
Year:2016

Bibliography

​Probing droplets with biological colloidal suspensions on smart surfaces by synchrotron radiation micro- and nano-beams
G. Marinaro, A. Accardo, N. Benseny-Cases, M. Burghammer, H. Castillo-Michel, M. Cotte, S. Dante, F. De Angelis, E. Di Cola, E. Di Fabrizio, C. Hauser and C. Riekel
Optics and Lasers in Engineering 76 (2016) 57-63

Abstract

Pub_PDB_2016

Droplets with colloidal biological suspensions evaporating on substrates with defined wetting properties generate confined environments for initiating aggregation and self-assembly processes. We describe smart micro- and nanostructured surfaces, optimized for probing single droplets and residues by synchrotron radiation micro- and nanobeam diffraction techniques. Applications are presented for Ac-IVD and β-amyloid (1-42) peptides capable of forming cross-β sheet structures. Complementary synchrotron radiation FTIR microspectroscopy addresses secondary structure formation. The high synchrotron radiation source brilliance enables fast raster-scan experiments.

DOI: 10.1016/j.optlaseng.2015.03.004

Keywords

Biological colloids Digital microfluidics Micro-/nano X-ray diffraction MicroFTIR Synchrotron radition
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